Bio Materials

BIO

Archieved

considerable improvements over current commercial surgical tissue sealants. This product, Gelatin-PhotoSeal™ is poised for commercial investment and development. This photo-crosslinking technology is also amenable for use in tissue engineering scaffolds. In the area of materials for stem cell expansion CSIRO working with the ASCC and in the CRC Polymers are developing an understanding of the stem cell niche and using this information have developed a manufacturable and scalable platform coating technology for the presentation of synthetic biological ligands on synthetic 2D and 3D surfaces for application to large scale stem cell expansion. Stem cell targets which this technology has been applied to are human haemopoietic, mesenchymal and embryonic stem cells. The technology has proved effective in a number of cases for the expansion of these cells over multiple passages in the absence of serum containing media, whilst maintaining the stem cell phenotype. The technology has been applied to a variety of cell culture ware formats including microcarrier particles. The surface coatings are fabricated using a variety of controlled free radical polymerisation methodologies (e.g. RAFT, ATRP) which allow for unprecedented control over polymeric coating properties and for end group modification and the incorporation of biologically relevant signalling molecules including.

Professor Peter Kingshott has returned to Australia to take up a position at Swinburne University of Technology in the Faculty of Engineering and Industrial Sciences (Biomedical Engineering). He will be employed within the Industrial Research Institute Swinburne (IRIS) and will set up his own research group within Polymer NanoInterface Engineering with a strong emphasis on Biomaterials applications. Peter left Australia in 1999 when he was employed as a postdoc at CSIRO Molecular Science, where he worked on developing new antifouling contact lens surfaces. Part of his research involved adapting the MALDI-TOF technique, together with other CSIRO scientists, to be able to directly detect and identify proteins adsorbed to surfaces. After leaving Australia Peter took up postdoc positions at both NESAC/BIO, University of Washington, USA, and RWTH Aachen, Germany. He then moved to Denmark to take up a Senior Scientist role at The Danish Polymer Centre, Riso National Laboratory, where he was employed for 5 ½ years working on projects relating to biointerface and polymer surfaces. In 2006 he moved to the Interdisciplinary Nanoscience Centre (iNANO) at Aarhus University as Associate Professor where his group set up the surface analysis facility (XPS and ToF-SIMS). In recent times Peter’s research has involved developing new surface patterning techniques based on colloidal crystal layers and surface functionalisation of polymer nanofibers for life science applications. He has published ~100 journal papers, 7 book chapters, and has 8 patents. Below are his new contact details. Please feel free to contact him if you are interested in his research.